Cargando…
Cytomegalovirus-Specific T Cells Persist at Very High Levels during Long-Term Antiretroviral Treatment of HIV Disease
BACKGROUND: In healthy, HIV seronegative, CMV seropositive adults, a large proportion of T cells are CMV-specific. High-level CMV-specific T cell responses are associated with accelerated immunologic aging (“immunosenesence”) in the elderly population. The impact of untreated and treated HIV infecti...
Autores principales: | Naeger, David M., Martin, Jeffrey N., Sinclair, Elizabeth, Hunt, Peter W., Bangsberg, David R., Hecht, Frederick, Hsue, Priscilla, McCune, Joseph M., Deeks, Steven G. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813282/ https://www.ncbi.nlm.nih.gov/pubmed/20126452 http://dx.doi.org/10.1371/journal.pone.0008886 |
Ejemplares similares
-
Impact of HIV on CD8+ T Cell CD57 Expression Is Distinct from That of CMV and Aging
por: Lee, Sulggi A., et al.
Publicado: (2014) -
Potential inflammatory consequences in HIV controllers
por: Hunt, Peter W, et al.
Publicado: (2010) -
Estimating the contribution of CD4 T cell subset proliferation and differentiation to HIV persistence
por: Reeves, Daniel B., et al.
Publicado: (2023) -
HIV-Infected Individuals with Low CD4/CD8 Ratio despite Effective Antiretroviral Therapy Exhibit Altered T Cell Subsets, Heightened CD8+ T Cell Activation, and Increased Risk of Non-AIDS Morbidity and Mortality
por: Serrano-Villar, Sergio, et al.
Publicado: (2014) -
Higher CD27(+)CD8(+) T Cells Percentages during Suppressive Antiretroviral Therapy Predict Greater Subsequent CD4(+) T Cell Recovery in Treated HIV Infection
por: Seu, Lillian, et al.
Publicado: (2013)