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Notch3 Cooperates With the EGFR Pathway to Modulate Apoptosis Through The Induction Of Bim
Notch signaling is a highly conserved pathway important for normal embryonic development and as well as cancer. We previously demonstrated a role for Notch3 in lung cancer pathogenesis. Notch3 inhibition resulted in tumor apoptosis and growth suppression. In vitro, these effects were enhanced when t...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813325/ https://www.ncbi.nlm.nih.gov/pubmed/19881544 http://dx.doi.org/10.1038/onc.2009.366 |