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Metabolic assessment of the action of targeted cancer therapeutics using magnetic resonance spectroscopy
Developing rational targeted cancer drugs requires the implementation of pharmacodynamic (PD), preferably non-invasive, biomarkers to aid response assessment and patient follow-up. Magnetic resonance spectroscopy (MRS) allows the non-invasive study of tumour metabolism. We describe the MRS-detectabl...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813738/ https://www.ncbi.nlm.nih.gov/pubmed/19935796 http://dx.doi.org/10.1038/sj.bjc.6605457 |