In Vivo Evaluation of α7 Nicotinic Acetylcholine Receptor Agonists [(11)C]A-582941 and [(11)C]A-844606 in Mice and Conscious Monkeys

BACKGROUND: The α7 nicotinic acetylcholine receptors (nAChRs) play an important role in the pathophysiology of neuropsychiatric diseases such as schizophrenia and Alzheimer's disease. The goal of this study was to evaluate the two carbon-11-labeled α7 nAChR agonists [(11)C]A-582941 and [(11)C]A...

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Detalles Bibliográficos
Autores principales: Toyohara, Jun, Ishiwata, Kiichi, Sakata, Muneyuki, Wu, Jin, Nishiyama, Shingo, Tsukada, Hideo, Hashimoto, Kenji
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813863/
https://www.ncbi.nlm.nih.gov/pubmed/20126539
http://dx.doi.org/10.1371/journal.pone.0008961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813863/
https://www.ncbi.nlm.nih.gov/pubmed/20126539
http://dx.doi.org/10.1371/journal.pone.0008961

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