CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity

BACKGROUND: Aberrant β-catenin signaling plays a key role in several cancer types, notably colon, liver and breast cancer. However approaches to modulate β-catenin activity for therapeutic purposes have proven elusive to date. METHODOLOGY: To uncover genetic dependencies in breast cancer cells that...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, So Young, Dunn, Ian F., Firestein, Ron, Gupta, Piyush, Wardwell, Leslie, Repich, Kara, Schinzel, Anna C., Wittner, Ben, Silver, Serena J., Root, David E., Boehm, Jesse S., Ramaswamy, Sridhar, Lander, Eric S., Hahn, William C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813871/
https://www.ncbi.nlm.nih.gov/pubmed/20126544
http://dx.doi.org/10.1371/journal.pone.0008979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813871/
https://www.ncbi.nlm.nih.gov/pubmed/20126544
http://dx.doi.org/10.1371/journal.pone.0008979

Ejemplares similares