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Vertebrate Lrig3-ErbB Interactions Occur In Vitro but Are Unlikely to Play a Role in Lrig3-Dependent Inner Ear Morphogenesis

BACKGROUND: The Lrig genes encode a family of transmembrane proteins that have been implicated in tumorigenesis, psoriasis, neural crest development, and complex tissue morphogenesis. Whether these diverse phenotypes reflect a single underlying cellular mechanism is not known. However, Lrig proteins...

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Detalles Bibliográficos
Autores principales: Abraira, Victoria E., Satoh, Takunori, Fekete, Donna M., Goodrich, Lisa V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813878/
https://www.ncbi.nlm.nih.gov/pubmed/20126551
http://dx.doi.org/10.1371/journal.pone.0008981