Influence of NFκB inhibitors on IL-1β-induced chemokine CXCL8 and -10 expression levels in intestinal epithelial cell lines: glucocorticoid ineffectiveness and paradoxical effect of PDTC

PURPOSE: Activation of intestinal epithelial cell (IEC) nuclear factor κB (NFκB) and the consequent chemokine upregulation are crucial events in inflammatory bowel disease (IBD) pathogenesis. Not much is known about the consequences of NFκB inhibition in terms of chemokine expression in intestinal c...

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Detalles Bibliográficos
Autores principales: Sunil, Yeruva, Ramadori, Giuliano, Raddatz, Dirk
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814033/
https://www.ncbi.nlm.nih.gov/pubmed/19921217
http://dx.doi.org/10.1007/s00384-009-0847-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814033/
https://www.ncbi.nlm.nih.gov/pubmed/19921217
http://dx.doi.org/10.1007/s00384-009-0847-3

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