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Tropomyosin Period 3 Is Essential for Enhancement of Isometric Tension in Thin Filament-Reconstituted Bovine Myocardium

Tropomyosin (Tm) consists of 7 quasiequivalent repeats known as “periods,” and its specific function may be associated with these periods. To test the hypothesis that either period 2 or 3 promotes force generation by inducing a positive allosteric effect on actin, we reconstituted the thin filament...

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Detalles Bibliográficos
Autores principales: Kawai, Masataka, Lu, Xiaoying, Hitchcock-DeGregori, Sarah E., Stanton, Kristen J., Wandling, Michael W.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814127/
https://www.ncbi.nlm.nih.gov/pubmed/20130792
http://dx.doi.org/10.1155/2009/380967