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IRES-based Vector Coexpressing FGF2 and Cyr61 Provides Synergistic and Safe Therapeutics of Lower Limb Ischemia

Due to the lack of an adequate conventional therapy against lower limb ischemia, gene transfer for therapeutic angiogenesis is seen as an attractive alternative. However, the possibility of side effects, due to the expression of large amounts of angiogenic factors, justifies the design of devices th...

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Detalles Bibliográficos
Autores principales: Rayssac, Audrey, Neveu, Charles, Pucelle, Mélanie, Van den Berghe, Loïc, Prado-Lourenco, Leonel, Arnal, Jean-François, Chaufour, Xavier, Prats, Anne-Catherine
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814383/
https://www.ncbi.nlm.nih.gov/pubmed/19738600
http://dx.doi.org/10.1038/mt.2009.211