Genomic Study of Replication Initiation in Human Chromosomes Reveals the Influence of Transcription Regulation and Chromatin Structure on Origin Selection

DNA replication in metazoans initiates from multiple chromosomal loci called origins. Currently, there are two methods to purify origin-centered nascent strands: lambda exonuclease digestion and anti-bromodeoxyuridine immunoprecipitation. Because both methods have unique strengths and limitations, w...

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Detalles Bibliográficos
Autores principales: Karnani, Neerja, Taylor, Christopher M., Malhotra, Ankit, Dutta, Anindya
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814785/
https://www.ncbi.nlm.nih.gov/pubmed/19955211
http://dx.doi.org/10.1091/mbc.E09-08-0707

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814785/
https://www.ncbi.nlm.nih.gov/pubmed/19955211
http://dx.doi.org/10.1091/mbc.E09-08-0707

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