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The Protective Role of Pregnane X Receptor in Lipopolysaccharide/D-galactosamine-induced Acute Liver Injury

The pregnane x receptor (PXR) is a nuclear receptor transcription factor regulating drug-metabolizing enzymes and transporters that facilitate xenobiotic and endobiotic detoxification. Recent studies demonstrate that PXR is important in abrogating intestinal tissue damage. This study examines the ro...

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Detalles Bibliográficos
Autores principales: Wang, Kun, Damjanov, Ivan, Wan, Yu-Jui Yvonne
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2814901/
https://www.ncbi.nlm.nih.gov/pubmed/19997066
http://dx.doi.org/10.1038/labinvest.2009.129