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Runx2 regulates survivin expression in prostate cancer cells

Previously we described that bone morphogenetic protein 7 (BMP7) could protect prostate cancer C4-2B cells from serum starvation-induced apoptosis via survivin induction. Here, for the first time, we identify Runx2 as a key regulator of survivin transcription. In C4-2B cells grown normally, suppress...

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Detalles Bibliográficos
Autores principales: Lim, Minyoung, Zhong, Chen, Yang, Shangxin, Bell, Adam M, Cohen, Michael B, Roy-Burman, Pradip
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815261/
https://www.ncbi.nlm.nih.gov/pubmed/19949374
http://dx.doi.org/10.1038/labinvest.2009.128