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Human mammary cancer progression model recapitulates methylation events associated with breast premalignancy

INTRODUCTION: We have previously identified a rare subpopulation of variant human mammary epithelial cells (vHMEC) with repressed p16(INK4A )that exist in disease-free women yet display premalignant properties, suggesting that they have engaged the process of malignant transformation. In order to ga...

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Detalles Bibliográficos
Autores principales: Dumont, Nancy, Crawford, Yongping G, Sigaroudinia, Mahvash, Nagrani, Shefali S, Wilson, Matthew B, Buehring, Gertrude C, Turashvili, Gulisa, Aparicio, Samuel, Gauthier, Mona L, Fordyce, Colleen A, McDermott, Kimberly M, Tlsty, Thea D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815551/
https://www.ncbi.nlm.nih.gov/pubmed/19995452
http://dx.doi.org/10.1186/bcr2457