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Human mammary cancer progression model recapitulates methylation events associated with breast premalignancy
INTRODUCTION: We have previously identified a rare subpopulation of variant human mammary epithelial cells (vHMEC) with repressed p16(INK4A )that exist in disease-free women yet display premalignant properties, suggesting that they have engaged the process of malignant transformation. In order to ga...
Autores principales: | , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815551/ https://www.ncbi.nlm.nih.gov/pubmed/19995452 http://dx.doi.org/10.1186/bcr2457 |