Differential Phospholipid Binding of α-Synuclein Variants Implicated in Parkinson’s Disease Revealed by Solution NMR Spectroscopy

[Image: see text] Three familial variants of the presynaptic protein α-synuclein (αS), A30P, E46K, and A53T, correlate with rare inherited Parkinson’s disease (PD), while wild-type αS is implicated in sporadic PD. The classic manifestation of both familiar and sporadic PD is the formation of fibrill...

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Detalles Bibliográficos
Autores principales: Bodner, Christina R., Maltsev, Alexander S., Dobson, Christopher M., Bax, Ad
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815556/
https://www.ncbi.nlm.nih.gov/pubmed/20041693
http://dx.doi.org/10.1021/bi901723p

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815556/
https://www.ncbi.nlm.nih.gov/pubmed/20041693
http://dx.doi.org/10.1021/bi901723p

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