Optimization of minimum set of protein–DNA interactions: a quasi exact solution with minimum over-fitting

Motivation: A major limitation in modeling protein interactions is the difficulty of assessing the over-fitting of the training set. Recently, an experimentally based approach that integrates crystallographic information of C2H2 zinc finger–DNA complexes with binding data from 11 mutants, 7 from EGR...

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Detalles Bibliográficos
Autores principales: Temiz, N. A., Trapp, A., Prokopyev, O. A., Camacho, C. J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815656/
https://www.ncbi.nlm.nih.gov/pubmed/19965883
http://dx.doi.org/10.1093/bioinformatics/btp664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815656/
https://www.ncbi.nlm.nih.gov/pubmed/19965883
http://dx.doi.org/10.1093/bioinformatics/btp664

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