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Estimating DNA coverage and abundance in metagenomes using a gamma approximation

Motivation: Shotgun sequencing generates large numbers of short DNA reads from either an isolated organism or, in the case of metagenomics projects, from the aggregate genome of a microbial community. These reads are then assembled based on overlapping sequences into larger, contiguous sequences (co...

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Detalles Bibliográficos
Autores principales: Hooper, Sean D., Dalevi, Daniel, Pati, Amrita, Mavromatis, Konstantinos, Ivanova, Natalia N., Kyrpides, Nikos C.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815663/
https://www.ncbi.nlm.nih.gov/pubmed/20008478
http://dx.doi.org/10.1093/bioinformatics/btp687