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DR-Integrator: a new analytic tool for integrating DNA copy number and gene expression data

Summary: DNA copy number alterations (CNA) frequently underlie gene expression changes by increasing or decreasing gene dosage. However, only a subset of genes with altered dosage exhibit concordant changes in gene expression. This subset is likely to be enriched for oncogenes and tumor suppressor g...

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Detalles Bibliográficos
Autores principales: Salari, Keyan, Tibshirani, Robert, Pollack, Jonathan R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815664/
https://www.ncbi.nlm.nih.gov/pubmed/20031972
http://dx.doi.org/10.1093/bioinformatics/btp702