Coupling transcriptional and post-transcriptional miRNA regulation in the control of cell fate

miRNAs function as a critical regulatory layer in development, differentiation, and the maintenance of cell fate. Depletion of miRNAs from embryonic stem cells impairs their differentiation capacity. Total elimination of miRNAs leads to premature senescence in normal cells and tissues through activa...

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Detalles Bibliográficos
Autores principales: Shalgi, Reut, Brosh, Ran, Oren, Moshe, Pilpel, Yitzhak, Rotter, Varda
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815735/
https://www.ncbi.nlm.nih.gov/pubmed/20157565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815735/
https://www.ncbi.nlm.nih.gov/pubmed/20157565

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