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Role of FGF19 induced FGFR4 activation in the regulation of glucose homeostasis

FGF19, FGF21, and FGF23 form a unique subfamily of fibroblast growth factors. Because they contain intra-molecular disulfide bonds and show reduced affinity toward heparan sulfate located in the extracellular space, it is thought that, in contrast to other FGFs, they function as endocrine hormones....

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Detalles Bibliográficos
Autores principales: Wu, Xinle, Li, Yang
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815751/
https://www.ncbi.nlm.nih.gov/pubmed/20157585