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The mtDNA mutator mouse: Dissecting mitochondrial involvement in aging

The role of mtDNA mutations in aging has been intensely debated because of their low abundance and correlative connection with aging. The creation of mtDNA mutator mice provided the first evidence that somatic mtDNA mutations have the capacity to cause a variety of aging phenotypes in mammals, and t...

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Detalles Bibliográficos
Autores principales: Edgar, Daniel, Trifunovic, Aleksandra
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815752/
https://www.ncbi.nlm.nih.gov/pubmed/20157586