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The mtDNA mutator mouse: Dissecting mitochondrial involvement in aging
The role of mtDNA mutations in aging has been intensely debated because of their low abundance and correlative connection with aging. The creation of mtDNA mutator mice provided the first evidence that somatic mtDNA mutations have the capacity to cause a variety of aging phenotypes in mammals, and t...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815752/ https://www.ncbi.nlm.nih.gov/pubmed/20157586 |