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Antioxidant N-acetyl-L-cysteine ameliorates symptoms of premature aging associated with the deficiency of the circadian protein BMAL1

Deficiency of the circadian clock protein BMAL1 leads to premature aging and increased levels of reactivate oxygen species in several tissues of mice. In order to investigate the role of oxidative stress in accelerated aging and development of age-related pathologies, we continuously administered th...

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Detalles Bibliográficos
Autores principales: Kondratov, Roman V., Vykhovanets, Olena, Kondratova, Anna A., Antoch, Marina P.
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815755/
https://www.ncbi.nlm.nih.gov/pubmed/20157581