Cargando…
Antioxidant N-acetyl-L-cysteine ameliorates symptoms of premature aging associated with the deficiency of the circadian protein BMAL1
Deficiency of the circadian clock protein BMAL1 leads to premature aging and increased levels of reactivate oxygen species in several tissues of mice. In order to investigate the role of oxidative stress in accelerated aging and development of age-related pathologies, we continuously administered th...
Autores principales: | Kondratov, Roman V., Vykhovanets, Olena, Kondratova, Anna A., Antoch, Marina P. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815755/ https://www.ncbi.nlm.nih.gov/pubmed/20157581 |
Ejemplares similares
-
BMAL1-dependent regulation of the mTOR signaling pathway delays aging
por: Khapre, Rohini V., et al.
Publicado: (2014) -
Circadian clock proteins control adaptation to novel environment and
memory formation
por: A.Kondratova, Anna, et al.
Publicado: (2010) -
Calorie restriction regulates circadian clock gene expression through BMAL1 dependent and independent mechanisms
por: Patel, Sonal A., et al.
Publicado: (2016) -
Deficiency of the Circadian Clock Gene Bmal1 Reduces Microglial Immunometabolism
por: Wang, Xiao-Lan, et al.
Publicado: (2020) -
Acetylation of BMAL1 by TIP60 controls BRD4-P-TEFb recruitment to circadian promoters
por: Petkau, Nikolai, et al.
Publicado: (2019)