Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density

The nutrient-sensing target of rapamycin (TOR) pathway appears to have a conserved role in regulating life span. This signaling network is complex, with many downstream physiological outputs, and thus the mechanisms underlying its age-related effects have not been elucidated fully. We demonstrated p...

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Detalles Bibliográficos
Autores principales: Pan, Yong, Shadel, Gerald S.
Formato: Texto
Lenguaje:English
Publicado: Impact Journals LLC 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815770/
https://www.ncbi.nlm.nih.gov/pubmed/20157595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815770/
https://www.ncbi.nlm.nih.gov/pubmed/20157595

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