Genetically-Defined Deficiency of Mannose-Binding Lectin Is Associated with Protection after Experimental Stroke in Mice and Outcome in Human Stroke

BACKGROUND: The complement system is a major effector of innate immunity that has been involved in stroke brain damage. Complement activation occurs through the classical, alternative and lectin pathways. The latter is initiated by mannose-binding lectin (MBL) and MBL-associated serine proteases (MA...

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Detalles Bibliográficos
Autores principales: Cervera, Alvaro, Planas, Anna M., Justicia, Carles, Urra, Xabier, Jensenius, Jens C., Torres, Ferran, Lozano, Francisco, Chamorro, Angel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815773/
https://www.ncbi.nlm.nih.gov/pubmed/20140243
http://dx.doi.org/10.1371/journal.pone.0008433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815773/
https://www.ncbi.nlm.nih.gov/pubmed/20140243
http://dx.doi.org/10.1371/journal.pone.0008433

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