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Complete-Proteome Mapping of Human Influenza A Adaptive Mutations: Implications for Human Transmissibility of Zoonotic Strains

BACKGROUND: There is widespread concern that H5N1 avian influenza A viruses will emerge as a pandemic threat, if they become capable of human-to-human (H2H) transmission. Avian strains lack this capability, which suggests that it requires important adaptive mutations. We performed a large-scale comp...

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Detalles Bibliográficos
Autores principales: Miotto, Olivo, Heiny, A. T., Albrecht, Randy, García-Sastre, Adolfo, Tan, Tin Wee, August, J. Thomas, Brusic, Vladimir
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815782/
https://www.ncbi.nlm.nih.gov/pubmed/20140252
http://dx.doi.org/10.1371/journal.pone.0009025