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Complete-Proteome Mapping of Human Influenza A Adaptive Mutations: Implications for Human Transmissibility of Zoonotic Strains
BACKGROUND: There is widespread concern that H5N1 avian influenza A viruses will emerge as a pandemic threat, if they become capable of human-to-human (H2H) transmission. Avian strains lack this capability, which suggests that it requires important adaptive mutations. We performed a large-scale comp...
Autores principales: | Miotto, Olivo, Heiny, A. T., Albrecht, Randy, García-Sastre, Adolfo, Tan, Tin Wee, August, J. Thomas, Brusic, Vladimir |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815782/ https://www.ncbi.nlm.nih.gov/pubmed/20140252 http://dx.doi.org/10.1371/journal.pone.0009025 |
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