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Lack of Sik1 in Mouse Embryonic Stem Cells Impairs Cardiomyogenesis by Down-Regulating the Cyclin-Dependent Kinase Inhibitor p57(kip2)

Sik1 (salt inducible kinase 1) is a serine/threonine kinase that belongs to the stress- and energy-sensing AMP-activated protein kinase family. During murine embryogenesis, sik1 marks the monolayer of future myocardial cells that will populate first the primitive ventricle, and later the primitive a...

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Detalles Bibliográficos
Autores principales: Romito, Antonio, Lonardo, Enza, Roma, Guglielmo, Minchiotti, Gabriella, Ballabio, Andrea, Cobellis, Gilda
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815785/
https://www.ncbi.nlm.nih.gov/pubmed/20140255
http://dx.doi.org/10.1371/journal.pone.0009029