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Contribution of Genome-Wide HCV Genetic Differences to Outcome of Interferon-Based Therapy in Caucasian American and African American Patients

BACKGROUND: Hepatitis C virus (HCV) has six major genotypes, and patients infected with genotype 1 respond less well to interferon-based therapy than other genotypes. African American patients respond to interferon α-based therapy at about half the rate of Caucasian Americans. The effect of HCV'...

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Detalles Bibliográficos
Autores principales: Donlin, Maureen J., Cannon, Nathan A., Aurora, Rajeev, Li, Jia, Wahed, Abdus S., Di Bisceglie, Adrian M., Tavis, John E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2815788/
https://www.ncbi.nlm.nih.gov/pubmed/20140258
http://dx.doi.org/10.1371/journal.pone.0009032