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Mechanism of expanding the decoding capacity of tRNAs by modification of uridines

One of the most prevalent base modifications involved in decoding is uridine 5-oxyacetic acid at the wobble position of tRNA. It has been known for several decades that this modification enables a single tRNA to decode all four codons in a degenerate codon box. We have determined structures of an an...

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Detalles Bibliográficos
Autores principales: Weixlbaumer, Albert, Murphy, Frank V., Dziergowska, Agnieszka, Malkiewicz, Andrzej, Vendeix, Franck A. P., Agris, Paul F., Ramakrishnan, V.
Formato: Texto
Lenguaje:English
Publicado: 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816034/
https://www.ncbi.nlm.nih.gov/pubmed/17496902
http://dx.doi.org/10.1038/nsmb1242