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VAV2 and VAV3 as Candidate Disease Genes for Spontaneous Glaucoma in Mice and Humans

BACKGROUND: Glaucoma is a leading cause of blindness worldwide. Nonetheless, the mechanism of its pathogenesis has not been well-elucidated, particularly at the molecular level, because of insufficient availability of experimental genetic animal models. METHODOLOGY/PRINCIPAL FINDINGS: Here we demons...

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Detalles Bibliográficos
Autores principales: Fujikawa, Keiko, Iwata, Takeshi, Inoue, Kaoru, Akahori, Masakazu, Kadotani, Hanako, Fukaya, Masahiro, Watanabe, Masahiko, Chang, Qing, Barnett, Edward M., Swat, Wojciech
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816215/
https://www.ncbi.nlm.nih.gov/pubmed/20140222
http://dx.doi.org/10.1371/journal.pone.0009050