F-Actin Binding Regions on the Androgen Receptor and Huntingtin Increase Aggregation and Alter Aggregate Characteristics

Protein aggregation is associated with neurodegeneration. Polyglutamine expansion diseases such as spinobulbar muscular atrophy and Huntington disease feature proteins that are destabilized by an expanded polyglutamine tract in their N-termini. It has previously been reported that intracellular aggr...

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Detalles Bibliográficos
Autores principales: Angeli, Suzanne, Shao, Jieya, Diamond, Marc I.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816219/
https://www.ncbi.nlm.nih.gov/pubmed/20140226
http://dx.doi.org/10.1371/journal.pone.0009053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816219/
https://www.ncbi.nlm.nih.gov/pubmed/20140226
http://dx.doi.org/10.1371/journal.pone.0009053

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