CpG Methylation of a Silent Controlling Element in the Murine A(vy) Allele Is Incomplete and Unresponsive to Methyl Donor Supplementation

BACKGROUND: The viable yellow allele of agouti (A(vy)) is remarkable for its unstable and partially heritable epigenetic state, which produces wide variation in phenotypes of isogenic mice. In the A(vy) allele an inserted intracisternal A particle (IAP) acts as a controlling element which deregulate...

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Detalles Bibliográficos
Autores principales: Cropley, Jennifer E., Suter, Catherine M., Beckman, Kenneth B., Martin, David I. K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816220/
https://www.ncbi.nlm.nih.gov/pubmed/20140227
http://dx.doi.org/10.1371/journal.pone.0009055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816220/
https://www.ncbi.nlm.nih.gov/pubmed/20140227
http://dx.doi.org/10.1371/journal.pone.0009055

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