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CpG Methylation of a Silent Controlling Element in the Murine A(vy) Allele Is Incomplete and Unresponsive to Methyl Donor Supplementation
BACKGROUND: The viable yellow allele of agouti (A(vy)) is remarkable for its unstable and partially heritable epigenetic state, which produces wide variation in phenotypes of isogenic mice. In the A(vy) allele an inserted intracisternal A particle (IAP) acts as a controlling element which deregulate...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816220/ https://www.ncbi.nlm.nih.gov/pubmed/20140227 http://dx.doi.org/10.1371/journal.pone.0009055 |