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p-Isothiocyanatobenzyl-desferrioxamine: a new bifunctional chelate for facile radiolabeling of monoclonal antibodies with zirconium-89 for immuno-PET imaging

PURPOSE: Immuno-PET is an emerging imaging tool for the selection of high potential antibodies (mAbs) for imaging and therapy. The positron emitter zirconium-89 ((89)Zr) has attractive characteristics for immuno-PET with intact mAbs. Previously, we have described a multi-step procedure for stable co...

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Detalles Bibliográficos
Autores principales: Perk, Lars R., Vosjan, Maria J. W. D., Visser, Gerard W. M., Budde, Marianne, Jurek, Paul, Kiefer, Garry E., van Dongen, Guus A. M. S.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816257/
https://www.ncbi.nlm.nih.gov/pubmed/19763566
http://dx.doi.org/10.1007/s00259-009-1263-1