Generation of Dopamine Neurons with Improved Cell Survival and Phenotype Maintenance Using a Degradation-Resistant Nurr1 Mutant

Nurr1 is a transcription factor specific for the development and maintenance of the midbrain dopamine (DA) neurons. Exogenous Nurr1 in neural precursor (NP) cells induces the differentiation of DA neurons in vitro that are capable of reversing motor dysfunctions in a rodent model for Parkinson disea...

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Detalles Bibliográficos
Autores principales: Jo, A-Young, Kim, Mi-Young, Lee, Hyun-Seob, Rhee, Yong-Hee, Lee, Jeong-Eun, Baek, Kwang-Hyun, Park, Chang-Hwan, Koh, Hyun-Chul, Shin, Incheol, Lee, Yong-Sung, Lee, Sang-Hun
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2009
Materias:
Tissue-Specific Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816355/
https://www.ncbi.nlm.nih.gov/pubmed/19522012
http://dx.doi.org/10.1002/stem.146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816355/
https://www.ncbi.nlm.nih.gov/pubmed/19522012
http://dx.doi.org/10.1002/stem.146

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