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Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene
BACKGROUND: There is a need to develop robust and clinically applicable gene expression signatures. Hypoxia is a key factor promoting solid tumour progression and resistance to therapy; a hypoxia signature has the potential to be not only prognostic but also to predict benefit from particular interv...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816644/ https://www.ncbi.nlm.nih.gov/pubmed/20087356 http://dx.doi.org/10.1038/sj.bjc.6605450 |