Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene

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BACKGROUND: There is a need to develop robust and clinically applicable gene expression signatures. Hypoxia is a key factor promoting solid tumour progression and resistance to therapy; a hypoxia signature has the potential to be not only prognostic but also to predict benefit from particular interv...

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Detalles Bibliográficos
Autores principales: Buffa, F M, Harris, A L, West, C M, Miller, C J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816644/
https://www.ncbi.nlm.nih.gov/pubmed/20087356
http://dx.doi.org/10.1038/sj.bjc.6605450

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