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Mutation analysis of the MSMB gene in familial prostate cancer

BACKGROUND: MSMB, a gene coding for β-microseminoprotein, has been identified as a candidate susceptibility gene for prostate cancer (PrCa) in two genome-wide association studies (GWAS). SNP rs10993994 is 2 bp upstream of the transcription initiation site of MSMB and was identified as an associated...

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Detalles Bibliográficos
Autores principales: Kote-Jarai, Z, Leongamornlert, D, Tymrakiewicz, M, Field, H, Guy, M, Al Olama, A A, Morrison, J, O'Brien, L, Wilkinson, R, Hall, A, Sawyer, E, Muir, K, Hamdy, F, Donovan, J, Neal, D, Easton, D, Eeles, R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816656/
https://www.ncbi.nlm.nih.gov/pubmed/19997100
http://dx.doi.org/10.1038/sj.bjc.6605485