Network-Based Elucidation of Human Disease Similarities Reveals Common Functional Modules Enriched for Pluripotent Drug Targets

Current work in elucidating relationships between diseases has largely been based on pre-existing knowledge of disease genes. Consequently, these studies are limited in their discovery of new and unknown disease relationships. We present the first quantitative framework to compare and contrast disea...

Descripción completa

Detalles Bibliográficos
Autores principales: Suthram, Silpa, Dudley, Joel T., Chiang, Annie P., Chen, Rong, Hastie, Trevor J., Butte, Atul J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816673/
https://www.ncbi.nlm.nih.gov/pubmed/20140234
http://dx.doi.org/10.1371/journal.pcbi.1000662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816673/
https://www.ncbi.nlm.nih.gov/pubmed/20140234
http://dx.doi.org/10.1371/journal.pcbi.1000662

Ejemplares similares