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Network-Based Elucidation of Human Disease Similarities Reveals Common Functional Modules Enriched for Pluripotent Drug Targets
Current work in elucidating relationships between diseases has largely been based on pre-existing knowledge of disease genes. Consequently, these studies are limited in their discovery of new and unknown disease relationships. We present the first quantitative framework to compare and contrast disea...
Autores principales: | Suthram, Silpa, Dudley, Joel T., Chiang, Annie P., Chen, Rong, Hastie, Trevor J., Butte, Atul J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816673/ https://www.ncbi.nlm.nih.gov/pubmed/20140234 http://dx.doi.org/10.1371/journal.pcbi.1000662 |
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