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DNA Binding of Centromere Protein C (CENPC) Is Stabilized by Single-Stranded RNA

Centromeres are the attachment points between the genome and the cytoskeleton: centromeres bind to kinetochores, which in turn bind to spindles and move chromosomes. Paradoxically, the DNA sequence of centromeres has little or no role in perpetuating kinetochores. As such they are striking examples...

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Detalles Bibliográficos
Autores principales: Du, Yaqing, Topp, Christopher N., Dawe, R. Kelly
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816676/
https://www.ncbi.nlm.nih.gov/pubmed/20140237
http://dx.doi.org/10.1371/journal.pgen.1000835