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A Humanized Anti-VEGF Rabbit Monoclonal Antibody Inhibits Angiogenesis and Blocks Tumor Growth in Xenograft Models

Rabbit antibodies have been widely used in research and diagnostics due to their high antigen specificity and affinity. Though these properties are also highly desirable for therapeutic applications, rabbit antibodies have remained untapped for human disease therapy. To evaluate the therapeutic pote...

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Detalles Bibliográficos
Autores principales: Yu, Yanlan, Lee, Pierre, Ke, Yaohuang, Zhang, Yongke, Yu, Qiu, Lee, Jonathan, Li, Mingzhen, Song, Jialiang, Chen, Jungang, Dai, Jihong, Couto, Fernando Jose Rebelo Do, An, Zhiqiang, Zhu, Weimin, Yu, Guo-Liang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816707/
https://www.ncbi.nlm.nih.gov/pubmed/20140208
http://dx.doi.org/10.1371/journal.pone.0009072