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A Humanized Anti-VEGF Rabbit Monoclonal Antibody Inhibits Angiogenesis and Blocks Tumor Growth in Xenograft Models
Rabbit antibodies have been widely used in research and diagnostics due to their high antigen specificity and affinity. Though these properties are also highly desirable for therapeutic applications, rabbit antibodies have remained untapped for human disease therapy. To evaluate the therapeutic pote...
Autores principales: | Yu, Yanlan, Lee, Pierre, Ke, Yaohuang, Zhang, Yongke, Yu, Qiu, Lee, Jonathan, Li, Mingzhen, Song, Jialiang, Chen, Jungang, Dai, Jihong, Couto, Fernando Jose Rebelo Do, An, Zhiqiang, Zhu, Weimin, Yu, Guo-Liang |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816707/ https://www.ncbi.nlm.nih.gov/pubmed/20140208 http://dx.doi.org/10.1371/journal.pone.0009072 |
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