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Genetic Variation at Selected SNPs in the Leptin Gene and Association of Alleles with Markers of Kidney Disease in a Xhosa Population of South Africa

BACKGROUND: Chronic kidney disease (CKD) is a significant public health problem that leads to end-stage renal disease (ESRD) with as many as 2 million people predicted to need therapy worldwide by 2010. Obesity is a risk factor for CKD and leptin, the obesity hormone, correlates with body fat mass a...

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Detalles Bibliográficos
Autores principales: Okpechi, Ikechi G., Rayner, Brian L., van der Merwe, Lize, Mayosi, Bongani M., Adeyemo, Adebowale, Tiffin, Nicki, Ramesar, Rajkumar
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816711/
https://www.ncbi.nlm.nih.gov/pubmed/20140086
http://dx.doi.org/10.1371/journal.pone.0009086