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Active Fragments from Pro- and Antiapoptotic BCL-2 Proteins Have Distinct Membrane Behavior Reflecting Their Functional Divergence

BACKGROUND: The BCL-2 family of proteins includes pro- and antiapoptotic members acting by controlling the permeabilization of mitochondria. Although the association of these proteins with the outer mitochondrial membrane is crucial for their function, little is known about the characteristics of th...

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Detalles Bibliográficos
Autores principales: Guillemin, Yannis, Lopez, Jonathan, Gimenez, Diana, Fuertes, Gustavo, Valero, Juan Garcia, Blum, Loïc, Gonzalo, Philippe, Salgado, Jesùs, Girard-Egrot, Agnès, Aouacheria, Abdel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816717/
https://www.ncbi.nlm.nih.gov/pubmed/20140092
http://dx.doi.org/10.1371/journal.pone.0009066