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A Comparison of Sample Size and Power in Case-Only Association Studies of Gene-Environment Interaction

Assuming continuous, normally distributed environmental and categorical genotype variables, the authors compare 6 case-only designs for tests of association in gene-environment interaction. Novel tests modeling the environmental variable as either the response or the predictor and allowing a genetic...

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Detalles Bibliográficos
Autores principales: Clarke, Geraldine M., Morris, Andrew P.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816730/
https://www.ncbi.nlm.nih.gov/pubmed/20047976
http://dx.doi.org/10.1093/aje/kwp398