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Stoichiometric Quantification of Akt Phosphorylation Using LC-MS/MS

[Image: see text] The Ptdlns-3-kinase (PI3-K) signaling pathway plays a vital role in cell survival, proliferation, apoptosis and differentiation in normal cells, as well as in diseases such as cancer and diabetes. Quantification of phospho-Akt is a standard way of assessing the activity of the PI3-...

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Detalles Bibliográficos
Autores principales: Atrih, Abdelmadjid, Turnock, Dan, Sellar, Grant, Thompson, Alastair, Feuerstein, Giora, Ferguson, Michael A. J., Huang, Jeffrey T.-J.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816933/
https://www.ncbi.nlm.nih.gov/pubmed/19902931
http://dx.doi.org/10.1021/pr900572h