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Stoichiometric Quantification of Akt Phosphorylation Using LC-MS/MS
[Image: see text] The Ptdlns-3-kinase (PI3-K) signaling pathway plays a vital role in cell survival, proliferation, apoptosis and differentiation in normal cells, as well as in diseases such as cancer and diabetes. Quantification of phospho-Akt is a standard way of assessing the activity of the PI3-...
Autores principales: | Atrih, Abdelmadjid, Turnock, Dan, Sellar, Grant, Thompson, Alastair, Feuerstein, Giora, Ferguson, Michael A. J., Huang, Jeffrey T.-J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816933/ https://www.ncbi.nlm.nih.gov/pubmed/19902931 http://dx.doi.org/10.1021/pr900572h |
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