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Regulation of Tumor Immune Surveillance and Tumor Immune Subversion by TGF-β

Transforming growth factor-β (TGF-β) is a highly pleiotropic cytokine playing pivotal roles in immune regulation. TGF-β facilitates tumor cell survival and metastasis by targeting multiple cellular components. Focusing on its immunosuppressive functions, TGF-β antagonists have been employed for canc...

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Detalles Bibliográficos
Autores principales: Park, Hae-Young, Wakefield, Lalage M, Mamura, Mizuko
Formato: Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816944/
https://www.ncbi.nlm.nih.gov/pubmed/20157598
http://dx.doi.org/10.4110/in.2009.9.4.122